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THE STUDY: Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity
https://pubmed.ncbi.nlm.nih.gov/35965199/
Diet-sensitive women had lower baseline adiposity, higher fasting insulin and triglycerides, and a greater number of ATP-III criteria for metabolic syndrome. Conversely in diet-resistant women, the exercise intervention improved body composition, skeletal muscle mitochondrial content and metabolism, with minimal effects in diet-sensitive women. In-depth analyses of muscle metabolomes revealed distinct group- and intervention- differences, including lower serine-associated sphingolipid synthesis in diet-resistant women following exercise training.
#FastingLifestyle #weightloss #exercise
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