Understanding Testosterone and Muscle Preservation | Shalin Shah

In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to explore the science, benefits, and future of testosterone therapy. Shalin has been a driving force behind bringing Kyzatrex, an FDA-approved oral testosterone, to market—making testosterone therapy more accessible and effective for both men and women. From breaking down misconceptions to advocating for better access to hormone therapy, this conversation sheds light on how testosterone plays a crucial role in overall health and wellness. This episode is a must-listen for anyone interested in health optimization, longevity, or understanding how testosterone therapy can impact overall quality of life. Who is Shalin Shah? Shalin Shah is a distinguished leader in the field of metabolic health, specializing in testosterone replacement therapy. As the Chief Executive Officer of Marius Pharmaceuticals, he was instrumental in the development and FDA approval of KYZATREX® (testosterone undecanoate) CIII Capsules, an oral testosterone treatment for adult men with low or no testosterone levels due to certain medical conditions. With a global investment background, Shalin transitioned into healthcare with a mission to revolutionize the industry through metabolic health. His leadership at Marius Pharmaceuticals is marked by innovative strategies that prioritize consumer access and education. Under his guidance, KYZATREX has been launched via consumer-focused channels that include preeminent national healthcare institutions, private-equity backed medical practices, and national telemedicine platforms. Shalin’s expertise extends beyond corporate leadership; he is an influential voice in longevity medicine and an advocate for reevaluating testosterone medication regulations. His efforts aim to reshape public perception and education on testosterone therapy and its significance for global health. He believes that oral testosterone replacement therapy has created a much-awaited paradigm shift which is critical for addressing the worldwide men’s (and women’s) health crisis, marked by declining testosterone levels and lower life expectancies. His message is that testosterone replacement therapy is not just about adding years to life, but also about adding life to years. 👉Apply to become a patient - https://drgabriellelyon.com/new-patient-inquiry/ 👉Join my weekly newsletter - https://institute-for-muscle-centric-medicine.ck.page/2ed23e2860 👉Get my book - https://drgabriellelyon.com/forever-strong/ Read More - A Phase III, Single-Arm, 6-month Trial of a Wide-Dose range Oral Testosterone Undecanoate Product - https://journals.sagepub.com/doi/full/10.1177/17562872241241864?af=R&ai=1gvoi&mi=3ricys The Effect of Testosterone Supplementation on Depression Symptoms in Hypogonadal Men - https://tandfonline.com/doi/full/10.3109/13685538.2011.606513 Testosterone Treatment to Prevent or Revert Type 2 Diabetes in Men - https://pubmed.ncbi.nlm.nih.gov/33338415/ Cardiovascular Safety of Testosterone-Replacement Therapy: https://nejm.org/doi/full/10.1056/NEJMoa2215025 This episode is brought to you by: Marius Pharmaceuticals - Discover more about accessible testosterone therapy options at Marius Pharmaceuticals. - https://mariuspharma.com Follow Shalin Shah - - Instagram: @themetabolicceo - LinkedIn: ShalinShah3 - X: @_ShalinShah Follow Marius Pharmaceuticals- - Website: https://mariuspharma.com - Instagram: @mariuspharmaceuticals - LinkedIn: Marius Pharmaceuticals Check out Kyzatrex - - Website: www.kyzatrex.com - Instagram: @kyzatrex_tu - Facebook: @Kyzatrex_TU Check out the ReThinkTestosterone - Website: www.rethinktestosterone.com - Instagram: @rethinktestosterone - Facebook: ReThink Testosterone - LinkedIn: ReThink Testosterone Check out the Testosterone Project - - Website: www.testosteroneproject.com - Instagram: @the_testosterone_project - Facebook: - LinkedIn: Find me at: - Instagram: @drgabriellelyon - Tik Tok: @drgabriellelyon Chapters 00:00:00 - Introduction to Oral Testosterone Therapy 00:07:25 - Understanding Testosterone Misconceptions and Risks 00:14:48 - The Role of Testosterone in Metabolic Health 00:21:55 - Testosterone Therapy: Historical Context and Challenges 00:29:13 - Oral vs Injectable Testosterone: Benefits and Comparisons 00:36:39 - Testosterone's Impact on Metabolic Syndrome and Diabetes 00:44:05 - Exploring Testosterone Therapy for Women 00:51:23 - The Future of Testosterone Therapy and Research 00:58:40 - Addressing Barriers to Testosterone Access and Education 01:05:55 - Kyzatrex: A New Approach to Testosterone Delivery 01:13:13 - Global Interest and Future Directions for Kyzatrex