STATS M254 - Statistical Methods in Comp Bio (Spring 2024) - Lec 4 (scRNA-seq normalization cont'd)

10x Genomics on normalization: https://www.10xgenomics.com/analysis-guides/single-cell-rna-seq-data-normalization SCTransform: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1874-1 DESeq2: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-014-0550-8 "Exaggerated false positives by popular differential expression methods when analyzing human population samples": https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02648-4 "Depth normalization for single-cell genomics count data": https://www.biorxiv.org/content/10.1101/2022.05.06.490859v1.full.pdf Variance stabilization: https://en.wikipedia.org/wiki/Variance-stabilizing_transformation SCnorm: https://www.nature.com/articles/nmeth.4263 Quantile regression: https://en.wikipedia.org/wiki/Quantile_regression