Longevity expert: Try this new type of fasting | Dr. Valter Longo and Prof. Tim Spector

🥑 Make smarter food choices. Become a member at http://zoe.com How old do you feel? While your birthday says one thing, your biological age—the health of your cells—might tell a very different story. And here’s the best part: unlike your chronological age, your biological age can go down. But how? For years, fasting has been celebrated as a key to longevity. Yet the challenge of skipping meals is enough to make most of us shy away. What if you could trick your body into reaping the rewards of fasting—without starving yourself? This week, we’re joined by Dr. Valter Longo, Director of the Longevity Institute at USC and one of TIME’s 50 most influential people in healthcare. Valter’s groundbreaking research on ageing and his FMD program have transformed how we think about health and longevity. Joining him is Professor Tim Spector, ZOE’s co-founder and one of the world’s top 100 most-cited scientists. 🌱 Try our new plant based wholefood supplement - Daily30: https://zoe.com/daily30?utm_medium=zoe_podcast&utm_source=podcast_platform&utm_campaign=d30 Follow ZOE on Instagram | https://www.instagram.com/zoe/ Timecodes 00:00 Fasting and biological age reversal 01:18 Quickfire questions: Can fasting slow aging? 02:29 Surprising discoveries about rejuvenating the body 03:39 Chronological vs biological age 05:20 Does this single gene mutation extend lifespan? 06:29 What twins teach us about aging and longevity 08:19 Are biological age tests reliable? 10:27 Dr. Longo explains the fasting mimicking diet 12:43 Can fasting help regenerate damaged organs? 15:42 The science behind nutrient sensing and aging 18:19 What is "maintenance mode" during fasting? 22:04 Genetics vs. lifestyle: Which impacts aging more? 24:24 Lab studies on longevity and fasting 28:30 What’s the ideal fasting window? 31:16 Does extreme fasting increase long-term health risks? 35:52 The fasting mimicking diet: How it works 45:41 Reversing kidney damage with fasting 47:10 Can a fasting protocol improve biological age by years? 55:08 Is a holistic approach to diet and fasting the key to longevity? 📚Books by our ZOE Scientists The Food For Life Cookbook | https://amzn.to/4amfIMX Every Body Should Know This by Dr Federica Amati | https://amzn.to/4blJsLg Food For Life by Prof. Tim Spector | https://amzn.to/4amZinu Free resources from ZOE: Live Healthier: Top 10 Tips From ZOE Science & Nutrition | https://zoe.com/freeguide Gut Guide - For a Healthier Microbiome in Weeks | https://zoe.com/gutguide Mentioned in today's episode Programmed longevity, youthspan, and juventology, 2018, published in Aging Cell https://pmc.ncbi.nlm.nih.gov/articles/PMC6351819/ Yeast Chronological Lifespan: Longevity Regulatory Genes and Mechanisms, 2022, published in Cells https://pubmed.ncbi.nlm.nih.gov/35626750/ Chronological Aging in Saccharomyces cerevisiae, 2012, published in Subcell Biochemistry https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048025/ Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population, 2014, published in Cell Metabolism https://pubmed.ncbi.nlm.nih.gov/24606898/ Growth Hormone Receptor Deficiency is Associated With a Major Reduction in Pro-aging Signaling, Cancer and Diabetes in Humans, 2012, published in Science Translational Medicine https://pmc.ncbi.nlm.nih.gov/articles/PMC3357623/#:~:text=It%20has%20been%20proposed%20that,markers%20of%20cancer%20and%20diabetes. Have feedback or a topic you'd like us to cover? Let us know here: https://gf6hx47iu5g.typeform.com/topicsuggestion Episode transcripts are available here: https://zoe.com/learn/category/podcasts