A Practical Guide to Echocardiographic Global Longitudinal Strain (GLS) by 2D Speckle Tracking

Vesna Mihajlovic MD Date: February 10, 2022 Objectives: 1. Understand the limitations of using LVEF as a marker of systolic function 2. Develop an understanding of how myocardial anatomy correlates to myocardial tissue deformation during contraction 3. Understand that strain is a measure of myocardial tissue deformation 4. Briefly summarize the clinical relevance of strain 5. Develop a gross understanding of the principles behind speckle tracking software 6. Demonstrate the technical steps required to obtain strain data 7. Identify normal and abnormal features on strain curves 8. Identify potential errors in strain analysis Reference: 1. Head-to-Head Comparison of Global Longitudinal Strain Measurements among Nine Different Vendors: The EACVI/ASE Inter-Vendor Comparison Study https://pubmed.ncbi.nlm.nih.gov/26209911/ 2. Global Longitudinal Strain for LV Function (ACC) https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2018/08/10/11/01/assessment-of-left-ventricular-global-longitudinal-strain